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Human β-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells.

Human β-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells.
Posted by Frank
AMP HBD-3 stimulates many functions of immune effector in myeloid cells and keratinocytes, especially through MAPK signaling cascade. Instead, HBD-3 reportedly neutralized the activation of T cells
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