Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells.

Imbalance between matrix synthesis and degradation is the hallmark of the degeneration of the intervertebral disc while contributing inflammatory cytokine imbalance. Bromodomain and extra-terminal domain (BET) family associated with the pathogenesis of inflammation, and inhibition of BRD4, an important member of the family BET, play an anti-inflammatory role in many diseases.

However, it remains elusive whether BRD4 play the same role in the nucleus pulposus (NP) cells and participates in the pathogenesis of intervertebral disc degeneration. The purpose of this study to examine whether inhibition of BRD4 matrix regulate metabolism by controlling autophagy and NLRP3 inflammasome activity. In addition, it investigated the relationship between nuclear factor kB (NF-kB) signaling, autophagy and NLRP3 inflammasome in NP cells.

Here, real-time polymerase chain reaction, Western blot analysis and GFP-LC3 adenoviral vector transduction in vitro were used, and it was revealed that BRD4 inhibition of matrix degradation and enhance ease of autophagy in the presence or absence of tumor necrosis factor α. In addition, p65 knockdown or treatment with JQ1 and Bay11-7082 indicate that inhibition of BRD4 NLRP3 inflammasome activity weakened through NF-kB signaling, while autophagy inhibition by bafilomycin A1 promoted matrix degradation and cell activity in the NP NLRP3 inflammasome.

In addition, the analysis of RNA expression in tissues BRD4 human NP further verified BRD4 destructive functions. Simply, BRD4 inhibition of matrix degradation Easing by increasing autophagy and suppress the activity of NLRP3 inflammasome through the NF-kB signaling in cells NP.

Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells.
Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells.

Links N Pressing interleukin-1β-induced biological effects in human osteoarthritic cartilage.

Osteoarthritis (OA) is a diarthrodial joint disease associated with proteolytic degradation of extracellular matrix under conditions of inflammation, pain and disability. Currently, no therapies to prevent, reverse or modulate the course of disease. This study aimed to evaluate the potential of regenerative Link N (LN) in human OA cartilage in inflammatory environment and determine whether the LN can influence the behavior associated pain in OA knee injury model rats. Osteo-chondro explants OA and OA chondrocytes treated with LN in the presence of interleukin-1β (IL-1β) to simulate the environment of osteoarthritic.

Von Frey quantitative polymerase chain reaction and Western blotting was performed to determine the effect of LN on matrix protein synthesis, catabolic enzymes, cytokines and nerve growth factor expression. Partial medial meniscectomy (PMM) was performed on the knee C57BL / 6 mice and, 12 weeks post-surgery, the rats were given 5 mg of intra-articular injection of LN or phosphate-buffered saline. A von Frey test carried out for 24 hours to measure the mechanical allodynia in the hind legs.

LN modulated proteoglycans and collagen synthesis in human OA cartilage by inhibiting the biological effects of IL-1β-induced. LN also suppressed the upregulation of IL-1β-induced cartilage-degrading enzymes and inflammatory molecules in OA chondrocytes. After an investigation of the canonical signaling pathway of IL-1β and nuclear factor kappa-light-chain-enhancer activated B cells (NF-kB), LN resulted in significantly inhibit NF-kB activation in a dose-dependent manner.

Interleukin 35 (IL35) Antibody

20-abx132303
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Interleukin 35 (IL35) Antibody

20-abx129830
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 35 (IL35) Antibody

20-abx101210
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Active Interleukin 35 (IL35)

4-APC008Hu01
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 35 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Recombinant Interleukin 35 (IL35)

4-RPC008Hu01
  • EUR 515.74
  • EUR 241.00
  • EUR 1659.04
  • EUR 619.68
  • EUR 1139.36
  • EUR 408.00
  • EUR 3997.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 35 expressed in: E.coli

Recombinant Interleukin 35 (IL35)

4-RPC008Mu01
  • EUR 537.25
  • EUR 247.00
  • EUR 1739.68
  • EUR 646.56
  • EUR 1193.12
  • EUR 422.00
  • EUR 4199.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Interleukin 35 expressed in: E.coli

Human Interleukin 35 (IL35) Protein

20-abx067529
  • EUR 718.00
  • EUR 286.00
  • EUR 2235.00
  • EUR 857.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 35 (IL35) Antibody Pair

20-abx370609
  • EUR 1748.00
  • EUR 1121.00
  • 10 × 96 tests
  • 5 × 96 tests

Interleukin 35 (IL35) Antibody (Biotin)

20-abx274523
  • EUR 356.00
  • EUR 203.00
  • EUR 926.00
  • EUR 467.00
  • EUR 300.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 35 (IL35) Antibody (Biotin)

20-abx274658
  • EUR 453.00
  • EUR 244.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Interleukin 35 (IL35) Protein

20-abx167498
  • EUR 746.00
  • EUR 300.00
  • EUR 2346.00
  • EUR 899.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Interleukin 35 (IL35) ELISA Kit

20-abx152044
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Interleukin 35 (IL35) ELISA Kit

20-abx154255
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Interleukin 35 (IL35) CLIA Kit

20-abx493363
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Sheep Interleukin 35 (IL35) ELISA Kit

abx257113-96tests 96 tests
EUR 864

Human Interleukin 35 (IL35) ELISA Kit

abx252675-96tests 96 tests
EUR 668

Mouse Interleukin 35 (IL35) ELISA Kit

abx254224-96tests 96 tests
EUR 668

Rat Interleukin 35 (IL35) ELISA Kit

abx363995-96tests 96 tests
EUR 786

Human Interleukin 35 ELISA Kit (IL35)

RK01676 96 Tests
EUR 573

Mouse Interleukin 35 ELISA Kit (IL35)

RK02945 96 Tests
EUR 521

Human Interleukin 35 (IL35) Protein (Active)

20-abx651393
  • EUR 759.00
  • EUR 300.00
  • EUR 2388.00
  • EUR 913.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 35 (IL35) Monoclonal Antibody (Human)

4-MAC008Hu21
  • EUR 255.00
  • EUR 2642.00
  • EUR 655.00
  • EUR 322.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35)

Mouse Interleukin 35 (IL35)CLIA Kit

SCC008Mu-10x96wellstestplate 10x96-wells test plate
EUR 5804.88
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35)CLIA Kit

SCC008Mu-1x48wellstestplate 1x48-wells test plate
EUR 565.7
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35)CLIA Kit

SCC008Mu-1x96wellstestplate 1x96-wells test plate
EUR 765.28
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35)CLIA Kit

SCC008Mu-5x96wellstestplate 5x96-wells test plate
EUR 3143.76
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35) CLIA Kit

4-SCC008Mu
  • EUR 5855.00
  • EUR 3144.00
  • EUR 766.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Interleukin 35 (IL35)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Human Interleukin 35 (IL35) ELISA Kit

SEC008Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Interleukin 35 (IL35) ELISA Kit

SEC008Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Interleukin 35 (IL35) ELISA Kit

SEC008Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Interleukin 35 (IL35) ELISA Kit

SEC008Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Interleukin 35 (IL35) ELISA Kit

4-SEC008Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Interleukin 35 (IL35) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Interleukin 35 (IL35) ELISA Kit

SEC008Mu-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35) ELISA Kit

SEC008Mu-1x48wellstestplate 1x48-wells test plate
EUR 488.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35) ELISA Kit

SEC008Mu-1x96wellstestplate 1x96-wells test plate
EUR 654.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35) ELISA Kit

SEC008Mu-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Interleukin 35 (IL35) ELISA Kit

4-SEC008Mu
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Interleukin 35 (IL35) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse)

4-PAC008Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35)

Interleukin 35 (IL35) Polyclonal Antibody (Human)

4-PAC008Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35)

ELISA kit for Human IL35 (Interleukin 35)

ELK2745 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Interleukin 35 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse IL35 (Interleukin 35)

ELK5768 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Interleukin 35 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Interleukin 35 (IL35) Monoclonal Antibody (Human), APC

4-MAC008Hu21-APC
  • EUR 358.00
  • EUR 3455.00
  • EUR 957.00
  • EUR 458.00
  • EUR 224.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with APC.

Interleukin 35 (IL35) Monoclonal Antibody (Human), Biotinylated

4-MAC008Hu21-Biotin
  • EUR 320.00
  • EUR 2592.00
  • EUR 760.00
  • EUR 394.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with Biotin.

Interleukin 35 (IL35) Monoclonal Antibody (Human), Cy3

4-MAC008Hu21-Cy3
  • EUR 435.00
  • EUR 4565.00
  • EUR 1235.00
  • EUR 569.00
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with Cy3.

Interleukin 35 (IL35) Monoclonal Antibody (Human), FITC

4-MAC008Hu21-FITC
  • EUR 306.00
  • EUR 2784.00
  • EUR 786.00
  • EUR 386.00
  • EUR 199.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with FITC.

Interleukin 35 (IL35) Monoclonal Antibody (Human), HRP

4-MAC008Hu21-HRP
  • EUR 327.00
  • EUR 3011.00
  • EUR 846.00
  • EUR 413.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with HRP.

Interleukin 35 (IL35) Monoclonal Antibody (Human), PE

4-MAC008Hu21-PE
  • EUR 306.00
  • EUR 2784.00
  • EUR 786.00
  • EUR 386.00
  • EUR 199.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with PE.

Interleukin 35 (IL35) Polyclonal Antibody (Human), Biotinylated

4-PAC008Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with Biotin.

Interleukin 35 (IL35) Polyclonal Antibody (Human), FITC

4-PAC008Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with FITC.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), Biotinylated

4-PAC008Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with Biotin.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), FITC

4-PAC008Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with FITC.

Interleukin 35 (IL35) Polyclonal Antibody (Human), APC

4-PAC008Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with APC.

Interleukin 35 (IL35) Polyclonal Antibody (Human), Cy3

4-PAC008Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with Cy3.

Interleukin 35 (IL35) Polyclonal Antibody (Human), HRP

4-PAC008Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with HRP.

Interleukin 35 (IL35) Polyclonal Antibody (Human), PE

4-PAC008Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with PE.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), APC

4-PAC008Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with APC.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), Cy3

4-PAC008Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with Cy3.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), HRP

4-PAC008Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with HRP.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), PE

4-PAC008Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with PE.

Human High Sensitive Interleukin 35 (IL35) CLIA Kit

20-abx490722
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human High Sensitive Interleukin 35 (IL35) ELISA Kit

20-abx258386
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human High Sensitive Interleukin 35 ELISA Kit (IL35)

RK01675 96 Tests
EUR 521

Interleukin 35 (IL35) Monoclonal Antibody (Human), APC-Cy7

4-MAC008Hu21-APC-Cy7
  • EUR 596.00
  • EUR 6790.00
  • EUR 1795.00
  • EUR 796.00
  • EUR 329.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with APC-Cy7.

Mini Samples Mouse Interleukin 35 (IL35) ELISA Kit

MEC008Mu-10x96wellstestplate 10x96-wells test plate
EUR 5804.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mini Samples Mouse Interleukin 35 (IL35) ELISA Kit

MEC008Mu-1x48wellstestplate 1x48-wells test plate
EUR 565.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mini Samples Mouse Interleukin 35 (IL35) ELISA Kit

MEC008Mu-1x96wellstestplate 1x96-wells test plate
EUR 765.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mini Samples Mouse Interleukin 35 (IL35) ELISA Kit

MEC008Mu-5x96wellstestplate 5x96-wells test plate
EUR 3143.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mini Samples Mouse Interleukin 35 (IL35) ELISA Kit

4-MEC008Mu
  • EUR 5855.00
  • EUR 3094.00
  • EUR 766.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mini Samples Mouse Interleukin 35 (IL35) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

High Sensitive Human Interleukin 35 (IL35) ELISA Kit

HEC008Hu-10x96wellstestplate 10x96-wells test plate
EUR 5189.65
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

High Sensitive Human Interleukin 35 (IL35) ELISA Kit

HEC008Hu-1x48wellstestplate 1x48-wells test plate
EUR 515.03
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

High Sensitive Human Interleukin 35 (IL35) ELISA Kit

HEC008Hu-1x96wellstestplate 1x96-wells test plate
EUR 692.9
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

High Sensitive Human Interleukin 35 (IL35) ELISA Kit

HEC008Hu-5x96wellstestplate 5x96-wells test plate
EUR 2818.05
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 35 (IL35) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

High Sensitive Human Interleukin 35 (IL35) ELISA Kit

4-HEC008Hu
  • EUR 5240.00
  • EUR 2769.00
  • EUR 693.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of High Sensitive Human Interleukin 35 (IL35) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Interleukin 35 (IL35) Polyclonal Antibody (Mouse), APC-Cy7

4-PAC008Mu01-APC-Cy7
  • EUR 583.00
  • EUR 6610.00
  • EUR 1750.00
  • EUR 778.00
  • EUR 324.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 35 (IL35). This antibody is labeled with APC-Cy7.

Interleukin 35 (IL35) Polyclonal Antibody (Human), APC-Cy7

4-PAC008Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 35 (IL35). This antibody is labeled with APC-Cy7.

Recombinant Human IL35 Protein, His, HEK 293-100ug

QP12423-100ug 100ug
EUR 998

Interleukin-35/IL-35

E21-M89 10ug
EUR 343

DiagNano Fluorophore Labeled Gold Nanoparticles, 35 nm

GFL-35 1 mL
EUR 1053

Mouse Interleukin 12A (IL35) CLIA Kit

20-abx190583
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Anti-IL6/ Interleukin 6 Antibody Clone IL6-Q3, Unconjugated-100ug

QDX34-100ug 100ug
EUR 403

Anti-IL6/ Interleukin 6 Antibody Clone IL6-Q2, Unconjugated-100ug

QDX35-100ug 100ug
EUR 403

Anti-IL6/ Interleukin 6 Antibody Clone IL6-Q1, Unconjugated-100ug

QDX36-100ug 100ug
EUR 403

Anti-IL6/ Interleukin 6 Antibody Clone IL6-Q8, Unconjugated-100ug

QDX37-100ug 100ug
EUR 403

Human Interleukin 35(IL-35)ELISA Kit

GA-E0002HM-48T 48T
EUR 289

Human Interleukin 35(IL-35)ELISA Kit

GA-E0002HM-96T 96T
EUR 466

Mouse Interleukin 35(IL-35)ELISA Kit    

GA-E0415MS-48T 48T
EUR 336

Mouse Interleukin 35(IL-35)ELISA Kit    

GA-E0415MS-96T 96T
EUR 534

Human Interleukin 35,IL-35 ELISA Kit

201-12-0043 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 35 (IL-35) CLIA Kit

abx197194-96tests 96 tests
EUR 825

Mouse Interleukin 35 (IL-35) CLIA Kit

abx197195-96tests 96 tests
EUR 825

Human Interleukin 35(IL-35) ELISA Kit

CSB-E13126h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 35 (IL-35) in samples from serum, cell culture supernates, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 35(IL-35) ELISA Kit

1-CSB-E13126h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 35(IL-35) in samples from serum, cell culture supernates, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Interleukin 35(IL-35) ELISA Kit

CSB-E13145m-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 35 (IL-35) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Interleukin 35(IL-35) ELISA Kit

1-CSB-E13145m
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 35(IL-35) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Interleukin 35(IL-35) ELISA Kit

CSB-E13652r-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 35 (IL-35) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Interleukin 35(IL-35) ELISA Kit

1-CSB-E13652r
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 35(IL-35) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Interleukin 35(IL-35)ELISA Kit

QY-E04269 96T
EUR 361

Human IL-35(Interleukin 35) ELISA Kit

EH3273 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

In addition, the LN suppressed mechanical allodynia in a rat model of OA PMM. The results support the concept that administration of LN can provide potential therapy in OA.