Cygnus Technologies, part of Maravai LifeSciences, is the biopharmaceutical industry’s partner in host cell protein (HCP) and other process-related impurity detection and analytics. In addition,
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Hydrogen sulfide (H2S) is now considered an endogenous gas mediator, which has been shown to be involved in many inflammatory countries. However, the mechanism of the proinflammatory function is
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The increase in cytokine levels such as TNF-α and IL-6 caused a surge in inflammation in acute ischemic heart disease (AIHD) .a dermcidin isoform-2 high level (DCN-2) occurs in AIHD will determine
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Background and Objectives: Trypsin urine (UTI) inhibitors, protein inhibiting diverse synthesized with hepatocytes, are considered to play an important role not only in organ injury protection during
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AMP HBD-3 stimulates many functions of immune effector in myeloid cells and keratinocytes, especially through MAPK signaling cascade. Instead, HBD-3 reportedly neutralized the activation of T cells
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Leflunomide is immunomodulator drugs with applications in managing rheumatoid arthritis. In this study, four new analogs (4A-D) A771726, active metabolites of Leflunomide were synthesized and
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Cultivation of kidney mesangial cells (MC) is easily established and widely used. MCs produce several complementary regulatory proteins (C). We studied whether MC synthesized components C (C3, C5,
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target receptors androgen therapy has emerged as an effective tool for managing prostate cancer (PCa). However, the frequent occurrence of therapy resistance is a major challenge in the clinical
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BACKGROUNDUntil now, a lot of effort used to enhance the regenerative potential of stem cells. In this study, we evaluated the hypothesis whether the modulation of autophagy could change
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AIMS / HYPOTHESISinflammatory signals and increase the synthesis of prostaglandins play a role during the development of diabetes. The prostaglandin D2 (PGD2) receptor, GPR44 / DP2, is highly